An interview with Ilya Prigogine* by Ioannis Zisis --- Greece, Astir Palace Hotel, Vouliagmeni, May 2000. *Ilya Prigogine was awarded with the Nobel Prize in Chemistry in 1977. He was director of Solvay Institute. He passed away at the age of 86, in May 28th 2003 at Brussels. Solon NGO would like to thankIoannis Antoniou, professor of Aristotle University of Thessaloniki,for his support and the translation of the interview as well.